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Objective of the study was to disentangle the role of nonsteroidal anti-inflammatory drugs ( NSAIDs ) in the increased risk of cardiovascular disease ( CVD ) among osteoarthritis patients. This lon ...


A study has compared efficacy and safety of subcutaneous Sarilumab ( Kevzara ) 200 mg and 150 mg every 2 weeks plus conventional synthetic disease-modifying antirheumatic drugs ( +csDMARDs ) versus o ...


Results from a phase 3 study evaluating Tanezumab 2.5 mg or 5 mg in patients with moderate-to-severe osteoarthritis ( OA ) pain were presented. Tanezumab 5 mg treatment arm met all three co-primary ...


A study presented at the Annual European Congress of Rheumatology ( EULAR 2018 ) has examined rates of malignancy in patients with rheumatoid arthritis ( RA ), excluding non-melanoma skin cancer ( NMS ...


Patients with systemic lupus erythematosus ( SLE ) are at risk of irreversible damage across multiple organ systems because of both active disease and medication toxicities. The severity and freque ...


Pain is one of the most important domains affecting health-related quality of life ( HRQoL ) in patients with psoriatic arthritis ( PsA ). Secukinumab ( Cosentyx ) has demonstrated rapid and sustain ...


Findings from two phase 3 studies, COAST-V and COAST-W, in adults with ankylosing spondylitis ( AS ), also referred to as radiographic axial spondyloarthritis ( axSpA ), were presented at the American ...


The aim of the study was to compare efficacy and safety of Sarilumab ( Kevzara ) monotherapy with Adalimumab ( Humira ) monotherapy in patients with active rheumatoid arthritis who should not continue ...


In 2016, the National Institute for Health and Care Excellence ( NICE ) approved the use of Belimumab ( Benlysta ) for the treatment of autoantibody-positive systemic lupus erythematosus ( SLE ). I ...


FKB327 ( Hulio ) is a proposed biosimilar of the Adalimumab Reference Product ( RP; Humira ). A randomized, double-blind, phase 3 study compared the efficacy, safety, pharmacokinetics and immunogeni ...


Psoriatic arthritis ( PsA ) is an inflammatory arthropathy, associated with skin and/or nail psoriasis. Real world data on efficacy and safety of TNF-alpha blockers in the elderly with psoriatic art ...


A study has evaluated the effectiveness of oral Glucosamine in subgroups of people with hip or knee osteoarthritis ( OA ) based on baseline pain severity, body mass index ( BMI ), sex, structural abno ...


Results from the phase 3 SELECT-MONOTHERAPY clinical trial were announced. This ongoing study evaluated Upadacitinib ( ABT-494 ), an investigational oral JAK1-selective inhibitor, as a monotherapy t ...


Results from the phase 3 SELECT-BEYOND clinical trial evaluating Upadacitinib ( ABT-494 ), an investigational oral JAK1-selective inhibitor, in patients with moderate to severe rheumatoid arthritis wh ...


Results of the landmark PRECISION ( Prospective Randomized Evaluation of Celecoxib Integrated Safety vs Ibuprofen Or Naproxen ) trial demonstrated similar rates of cardiovascular risk in patients trea ...