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Search results for "Methotrexate"

A Phase III clinical study of Rituximab ( Rituxan ) met its primary endpoint of a greater proportion of Rituximab-treated patients achieving an American College of Rheumatology ( ACR ) 20 response at ...


Patients with rheumatoid arthritis, whose joint damage is inhibited through a combination therapy of Adalimumab ( Humira ) and Methotrexate early in the course of their disease are less likely to expe ...


Preliminary results from a large randomized clinical trial of Rituximab ( Rituxan ) in rheumatoid arthritis showed that a greater proportion of patients treated with a single course of Rituximab, with ...


Combined treatment with Adalimumab ( Humira ) and Methotrexate is about five times more effective than Methotrexate alone in people with long-standing rheumatoid arthritis. In six randomized contro ...


The course of rheumatoid arthritis ( RA ) can vary considerably, from mild to crippling, and is difficult to predict. On the strength of patient case histories and clinical trials, rheumatologists ha ...


The FDA ( U.S. Food and Drug Administration ) approved Humira ( Adalimumab ) for first-line treatment of recent onset moderate to severe rheumatoid arthritis ( RA ). The approval offers RA patients a ...


Data from a long-term blinded study of anti-TNF agent in patients with rheumatoid arthritis demonstrated that more than three quarters of patients treated with Enbrel ( Etanercept ) plus Methotrexate ...


Two-year study of patients with early, aggressive disease demonstrates significantly superior results of anti-TNF plus DMARD therapy over either therapy alone. A chronic and potentially crippling i ...


The FDA ( U.S. Food and Drug Administration ) has approved the therapeutic antibody Rituxan ( Rituximab ) in combination with Methotrexate to reduce signs and symptoms in adult patients with moderatel ...


Rheumatoid arthritis is associated with increased occurrence of lymphoma, which plays an integral role in the body's ability to fight infection. While various studies have affirmed this link, none hav ...


Marked by chronic inflammation of the joints and tissue, rheumatoid arthritis is a painful and potentially disabling autoimmune disease. A wealth of research supports early aggressive treatment with d ...


Treatment with Belimumab ( Benlysta ) resulted in a sustained improvement of systemic lupus erythematosus ( SLE or lupus ) disease activity in 46% of patients at week 52.Historically, it has been diff ...


Treatment with Denosumab 60 mg and 180 mg, ( associated with Methotrexate ) reduces the progression of bone erosion. Denosumab is a fully human monoclonal antibody which binds to and inhibits the R ...


To manage the painful and incapacitating symptoms of rheumatoid arthritis ( RA ), a chronic, inflammatory joint disease, the majority of patients rely on disease-modifying antirheumatic drugs ( DMARDs ...


Rheumatoid arthritis patients who failed to respond to initial treatment with Rituximab ( MabThera, Rituxan ) ( a chimeric monoclonal antibody against the protein CD20 ) can still be successfully re-t ...