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Search results for "Rheumatoid arthritis"

Long-term use of anti-TNF-alpha agents can lead to the development of autoantibodies. Infliximab ( Remicade ) is a chimeric human-murine monoclonal antibody that inhibits TNF-alpha. Investigator ...


A study, led by Nancy A. Nussmeier at the Texas Heart Institute, St. Luke's Episcopal Hospital, in Houston, assessed the safety of Valdecoxib ( Bextra ) and its intravenous prodrug Parecoxib ( Dynasta ...


A prospective cohort study found that Tumour Necrosis Factor alpha ( TNF-alpha ) blocking agents, trigger skin conditions in 25% of patients with rheumatoid arthtitis. TNF-alpha blocking agents has ...


A Phase III clinical study of Rituximab ( Rituxan ) met its primary endpoint of a greater proportion of Rituximab-treated patients achieving an American College of Rheumatology ( ACR ) 20 response at ...


Researchers from the Baylor Institute for Immunology Research in Dallas report on the successful treatment of children with systemic onset juvenile idiopathic arthritis ( SoJIA ) in whom previous ther ...


Study suggests continuous NSAID treatment more effectively reduces X-Ray progression than intermittent treatment. A widely under-recognized form of arthritis, ankylosing spondylitis ( AS ) is a chr ...


Drugs blocking the action of TNF ( Tumor Necrosis Factor ) have shown promise in the early treatment of rheumatoid arthritis. To expand the understanding of TNF's function in chronic inflammatory ...


Patients with rheumatoid arthritis, whose joint damage is inhibited through a combination therapy of Adalimumab ( Humira ) and Methotrexate early in the course of their disease are less likely to expe ...


Preliminary results from a large randomized clinical trial of Rituximab ( Rituxan ) in rheumatoid arthritis showed that a greater proportion of patients treated with a single course of Rituximab, with ...


A research has showed that gene therapy for arthritis and other non-terminal, debilitating conditions and diseases is both feasible and safe. This is the world’s first gene therapy trial in patient ...


The cellular signaling protein Wnt, which is involved in embryonic development and cancer, contributes to disease progression of both rheumatoid arthritis and osteoarthritis. Wnt is best known as a ...


Combined treatment with Adalimumab ( Humira ) and Methotrexate is about five times more effective than Methotrexate alone in people with long-standing rheumatoid arthritis. In six randomized contro ...


Researchers at the University of Manchester's Medical School have discovered that eating more brightly-coloured fruits and vegetables like oranges, carrots and sweetcorn may help reduce the risk of de ...


Women treated with aromatase inhibitors often experience joint pain and musculoskeletal aching --severe enough, in some cases, to make them stop the treatment. Two researchers, David T. Felson, of ...


The course of rheumatoid arthritis ( RA ) can vary considerably, from mild to crippling, and is difficult to predict. On the strength of patient case histories and clinical trials, rheumatologists ha ...