Rheumatology.net

Rheumatology Xagena

Xagena Mappa
Medical Meeting
Ematobase.it
Reumabase.it

Interleukin-17A ( IL-17A ) is a key cytokine in the pathogenesis of psoriatic disease of the skin and joints. In phase 3 trials, Secukinumab ( Cosentyx ), a fully human anti-IL-17A monoclonal antibody ...


Since the publication of the European League Against Rheumatism ( EULAR ) recommendations for the pharmacological treatment of psoriatic arthritis ( PsA ) in 2012, new evidence and new therapeutic age ...


Most incident cases of psoriatic arthritis ( PsA ) present among patients with pre-existing psoriasis, and because of the high absolute prevalence of psoriatic arthritis among psoriasis patients this ...


Patients with rheumatoid arthritis ( RA ) and co-existent bronchiectasis ( BRRA ) have a five-fold increased mortality compared to rheumatoid arthritis alone. Yet previous studies have found no differ ...


Positive data from the phase IIb BALANCE-I and BALANCE-II trials for experimental JAK1 inhibitor, ABT-494 in rheumatoid arthritis were announced. The BALANCE-I study evaluated one of four twice-da ...


Stimulators of the soluble guanylate cyclase ( sGC ) have recently been shown to inhibit transforming growth factor-beta ( TGF-beta ) signalling. Researchers aimed to demonstrate that Riociguat ( ...


Enhanced cardiovascular risk in ankylosing spondylitis provides a strong rationale for early therapeutical intervention. In view of the proven benefit of statins in atherosclerotic vascular disease, a ...


Patients with rheumatoid arthritis and carotid artery plaques have increased risk of acute coronary syndromes. Statin treatment with low density lipoprotein cholesterol ( LDL-c ) goal  less than or eq ...


The objective of a study was to determine the safety of Ocrelizumab in patients with rheumatoid arthritis. An analysis of the double-blind, placebo-controlled periods and long-term follow-up of 4 O ...


The results of several new sub-analyses of the phase IIIb AVERT ( Assessing Very Early Rheumatoid arthritis Treatment ) trial that investigated the use of Abatacept ( Orencia ) plus Methotrexate ( MTX ...


Rheumatoid arthritis is associated with increased cardiovascular morbidity and mortality attributed to traditional cardiovascular risk factors and/or the chronic systemic inflammation. Researchers ...


Etanercept ( Enbrel ) has been widely applied in the treatment of ankylosing spondylitis ( AS ). Previous meta-analyses have focused on comparing the differences in clinical outcomes between Etanercep ...


A study has evaluated the efficacy and safety of Adalimumab ( Humira ) in patients with juvenile idiopathic arthritis ( JIA ). Baseline demographic and clinical characteristics and disease activity ...


A study has investigated whether use of Adalimumab ( Humira ) decreases the frequency of attacks of anterior uveitis in patients with ankylosing spondylitis. Consecutive patients with ankylosing sp ...


High body mass index ( BMI ) is associated with increased risk of osteoarthritis ( OA ) and reduced risk of fragility fracture. However, the relationship between fragility fracture and osteoarthritis ...